The important developments in cancer therapy in the past few years have been those regarding growth of systemic therapeutics. With enhancements in response rates in solid tumors, chances have appeared to improve the effectiveness of surgery. Administration of systemic therapy prior to surgery- neoadjuvant chemotherapy - presents one of the means by which clinicians have successfully shortened the extent of surgery and, in some cases, positively affected the clinical outcomes. The book collects works by expert clinicians from various disciplines of the field presenting a study of current advances in the function of neoadjuvant chemotherapy in different types of tumors.