Parkinson's disease is a central nervous system disorder. It is a degenerative disorder. It primarily affects the motor system. Its symptoms include shaking, rigidity, slowness of movement, sleeping problems, etc. Its causes are still unknown but are associated with environmental and genetic factors. Environmental factors involve exposure to pesticides and genetic factors include mutation. The diagnosis of this disease is based on a neurological examination through computed tomography and magnetic resonance imaging. The prevention and management of Parkinson's disease involves the use of antioxidants, and certain medications such as dopamine agonists, MAO-B inhibitors, amantadine and anticholinergics. Certain rehabilitation exercises like diaphragmatic breathing, rhythmic initiation, etc. can also be used for its management. This book provides comprehensive insights into Parkinson's disease and its diagnosis and treatment. It will also provide interesting topics for research which interested readers can take up. The book is appropriate for students seeking detailed information in this area as well as for experts.