Cases & Concepts Step 1: Pathophysiology Review helps medical students prepare for USMLE Step 1 by combining basic science topics with clinical data. Working through 88 clinical cases, the reader gains experience analyzing cases, learns classic presentations of common diseases and syndromes, and integrates basic science concepts with clinical applications. Sections cover cardiovascular, pulmonary, renal, gastrointestinal, hematology, oncology, endocrinology, rheumatology, reproduction, and neuroscience. Cases are followed by USMLE-style questions with answers and rationales. Thumbnail and Key Concept boxes highlight key facts. A companion website offers fully searchable text online.