The Sixth Edition continues to exemplify the principles outlined in the Vision and Change in Undergraduate Biology Education report. The text's unique BioSkills section is now placed after Chapter 1 to help students develop key skills needed to become a scientist, new OMaking ModelsO boxes guide learners in interpreting and creating models, and new OPut It all TogetherO case studies conclude each chapter and help students see connections between chapter content and current, real-world research questions.