This book contains papers based on the fourteen lectures presented at the NATO Advanced Study Institute 'Information Security and Related Combinatorics', held in Opatija, Croatia, May 31 - June 11, 2010. The conference was widely attended by students and junior scientists from throughout Europe and the USA. The theme addressed by these papers is combinatorial mathematics, as used in applications related to information security, cryptography and coding theory. Together they cover several topics subject to current research in the field. The volume will be of interest to mathematicians, computer.