Title Page -- Preface -- Foreword -- Methodology for Assessment of Medical IT-Based Systems - in an Organisational Context -- CONTENTS -- Part I: Introduction -- 1 Background Information -- 1.1 Formulation of the Problem -- 1.2 Assessment Methodologies in the Literature -- 1.3 Basis for Accomplishment of the Present Study -- 1.4 What is special about the Medical Application Domain? -- 2 Study Objectives -- 2.1 Formulation of Objectives -- 2.2 Delimitation -- 2.3 Overall Strategy and Approach -- 2.4 Discussion -- 3 Central Terminology -- 3.1 Quality Assessment Concepts -- 3.2 Metrology Concepts -- Part II: Two Step Development of an Assessment Methodology -- 4 KAVAS's Evaluation Methodology for Knowledge-Based Systems (The 1st Goal) -- 4.1 Introduction -- 4.2 Methods -- 4.3 Results: KAVAS's Evaluation Methodology for Knowledge-Based Systems -- 4.4 Results from Application of the Evaluation Methodology -- 4.5 Discussion and Conclusion -- 5 ISAR's Generalised Methodology for Assessment of IT-based Systems (The 2nd Goal) -- 5.1 Introduction -- 5.2 Methods -- 5.3 Results: The Generalised Evaluation Methodology -- 5.4 Results from Verification of the Generalised Evaluation Methodology -- 5.5 Discussion and Conclusion -- Part III: The Case Study -- 6 Methodology for the Case Study -- 6.1 Introduction -- 6.2 Method I: The Functionality Assessment Methodology -- 6.3 Method II: The Logical Framework Approach -- 6.4 Results: The Methodology for the Case Study -- 6.5 Discussion -- 7 Experimental Observations for the Case Study -- 7.1 Notes on the Overall Experimental Approach -- 7.2 Results: Functionality Assessment Methodology, Steps 1 to 4 -- 7.3 Results: Logical Framework Approach, Steps 1 and 2 -- 7.4 Discussion -- Part IV: Synthesis of the Dynamic Assessment Methodology -- 10 Role and Contents of User Requirements Documents -- 10.1 Introduction