This study is devoted to the Sunyaev-Zeldovich (S-Z) effect, and important related topics in cluster and CMB research. S-Z science is about to be significantly enhanced by unique, multi-faceted cluster and cosmological yield, at a level of precision in accord with the high standards of the current era that was heralded by spectacular achievements in cosmological CMB research. The pedagogical reviews and technical seminars included in this volume represent most of the important current topics in S-Z work and in the astrophysics of clusters. The publication touches upon all relevant aspects of t.