The global authority of the West is no longer unchallenged; the Western worldview is no longer accepted as universal. It is increasingly being questioned by emerging economies around the globe that are developing their own standards. If we look at the geographical positions of the emerging economies, it appears that they collectively form a belt around the southern part of the globe: “The Global Southern Belt.” The Westerncentric world is fading into a multicentered world in which many countries and even more important, “a world of cities” will set the tone in global matters. The game changers will be the countries and cities of the Global Southern Belt, which will reshape our world in the decades to come. Like John Naisbitt’s international bestselling book Megatrends in 1982, Global Game Change offers an indispensable roadmap of the transforming global landscape. It replaces the uncertainty of rapid change with a description of the future.