A clinical approach towards periodontal disease has been described in this up-to-date book. The aim of this book is to cater to modern practitioners as well as students and educators in the field of periodontology. An elucidation of the contemporary concepts illustrating the complex interactions of multiple genotypes, microbial fingerprint and host modulations has been presented in this book. Furthermore, an analysis of the clinical outcome of the disease's progression, as influenced by the epigenetic factors, has been provided. This elucidative book also provides in-depth explanations of the rising concepts on periodontitis as a bilateral modulating factor and as a risk factor for several systemic diseases.