The area of renal cell cancer has experienced tremendous resurgence. This book provides a synopsis of latest research and innovative ideas for the future in this rapidly changing field, which encompasses medicine, surgery, radiation oncology, basic science, pathology, radiology, and supportive care. The book encompasses tumor and molecular biology, surgery mechanisms, radiation therapy, challenges in the treatment of renal carcinoma, oxidative stress and steroids receptors in carcinoma. The objective was to present a detailed account that would act as a credible source for scientists and clinicians; and interpret the domain for trainees in surgery, medicine, radiation oncology and pathology. This book targets clinicians, scientists and professionals who have interest in renal cell cancer.