This report documents verification and application of a modeling approach to the detailed inelastic analysis of large diameter, thin walled piping configurations typical of liquid metal cooled reactor primary piping, subjected to mechanical loads and thermal shock, with intermediate periods of creep under constant load and temperature.The primary purposes of the project are fourfold: first, to provide verification of the modeling approach; second, to investigate the importance of straight pipe/pipe bend interaction effects (end effects) in realistic cases; third, to demonstrate and compare a more economic analysis method that neglects end effects; and fourth, to show that this level of analysis effort is feasible even for preliminary piping system analysis.